From 101:

Take San Antonio exit West,
go right on Charleston.  
Charleston becomes
Arastradero as it passes El
Camino.  Go past Foothill
Expressway and make an
immediate left onto Manuela.  
Stay to the left fork, pass the
synagogue.  We're on the left.

From 280:

Take Page Mill exit east,
make a right at Deer Creek.  
Left at Arastradero, and just
before you get to Foothill
Expressway, make a right at
Maneula.  Stay to the left
fork, pass the synagogue.  
We're on the left.